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Friday, October 12, 2018

Got Fluoride? Got Thyroid Problems!

Got Fluoride? Got Thyroid Problems!

Fluoride exposure and thyroid function among adults living in Canada:Effect modification by iodine status
Ashley J. Malina,b,, Julia Riddellb, Hugh McCaguec, Christine Tillb
a Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1057, New York 10029, NY, USA b Psychology Department, Faculty of Health, York University, 4700 Keele St, Toronto M3J 1P3, ON, Canada
c Institute for Social Research, York University, 242A-4700 Keele St, Toronto, ON, Canada, M3J 1P3


  • Higher urinary fluoride levels are not associated with higher TSH levels in the general population of adults living in Canada.
  • Iodine status modifies the relationship between urinary fluoride and TSH levels.
  • Adults in Canada who have moderate-to-severe iodine deficiencies and higher urinary fluoride tend to have higher TSH levels.
BACKGROUND: Fluoride exposure has the potential to disrupt thyroid functioning, though adequate iodine intake may mitigate this effect. This is the first population-based study to examine the impact of chronic low-level fluoride exposure on thyroid function, while considering iodine status. The objective of this study was to determine whether urinary iodine status modifies the effect of fluoride exposure on thyroid stimulating hormone (TSH) levels.

METHODS: This cross-sectional study utilized weighted population-based data from Cycle 3 (2012?2013) of the Canadian Health Measures Survey (CHMS). Information was collected via a home interview and a visit to a mobile examination centre. The weighted sample represented 6,914,124 adults in Canada aged 18–79 who were not taking any thyroid-related medication. Urinary fluoride concentrations were measured in spot samples using an ion selective electrode and adjusted for specific gravity (UFSG). Serum TSH levels provided a measure of thyroid function. Multivariable regression analyses examined the relationship between UFSG and TSH, controlling for covariates.

RESULTS: Approximately 17.8% of participants fell in the moderately-to-severely iodine deficient range. The mean (SD) age of the sample was 46.5 (15.6) years and the median UFSG concentration was 0.74?mg/L. Among iodine deficient adults, a 1?mg/L increase in UFSG was associated with a 0.35 mIU/L increase in TSH [95% CI: 0.06, 0.64; p?=?0.01, one-tailed].

CONCLUSIONS: Adults living in Canada who have moderate-to-severe iodine deficiencies and higher levels of urinary fluoride may be at an increased risk for underactive thyroid gland activity.

1 comment:

  1. Fluoride is a poison. Fluoride was poison yesterday. Fluoride is poison today. Fluoride will be poison tomorrow. "The Devil's Poison" is the nick name of the substance Templeton water department adds to our public water supply. The poison is added to our water so that big corporations can save money on hazardous waste disposal and litigation concerning fluoride poisoning. When in doubt get it out.